DR. GAURAV GARG

, DR MRITTIKA SEN, Dr. SANTOSH G. HONAVAR

Abstract

Sebaceous gland carcinoma (SGCa) of the eyelid, a potentially fatal neoplasm, is notorious to be misdiagnosed as chalazion or blepharitis, resulting in delayed diagnosis and inappropriate management. There are no established clinical criteria for a general ophthalmologist to differentiate it from simulating conditions. Intraepithelial spread is clinically difficult to recognize, thus the importance of wide excision with intraoperative margin control and conjunctival map biopsy as the treatment of choice. Wide excision leaves behind a large eyelid coloboma, which needs to be optimally reconstructed with due attention to the eyelid function and aesthetics. This video focuses on the varied spectrum of clinical manifestations of SGCa, its masquarades, clinical signs to differentiate simulating conditions, and the surgical algorithm for optimal management. Early diagnosis and protocol-based management can minimize the risk of local tumor recurrence and systemic metastasis in SGCa.