Dr.Arushi Garg

Dr.Pooja Jain, Dr. NAREN SHETTY, Dr. HIMANSHU MATALIA

Abstract

Purpose:To study densitometric pattern and progression of haze after accelerated CXL (A-CXL) using hydroxypropyl methylcellulose(HPMC) riboflavin dye. Methods: Retrospective case series of 30 eyes with progressive keratoconus, that underwent ACXL (18 mW/cm2 for 5 minutes) using >1% HPMC dye. Visual outcome, keratometry and corneal densitometry (grey scale units) on Scheimpflug tomography was measured preoperatively and postoperative 1, 3 and 6 months. Statistical analysis was done using T-test. Results: Preoperative mean total corneal densitometry in central 6mm increased significantly in 0-2mm and 2-6mm zone to postoperative 1 month(p<0.01) and 3 months (p<0.01) and returned to baseline levels by 6 months. 18 eyes showed haze and increased densitometry in central posterior stroma and anterior mid-periphery at 1 month, which completely resolved by 6 months. Conclusion: A-CXL with HPMC dye temporarily shows a distinct pattern of central deep stromal and mid-peripheral haze at 1 month.