Dr. DEEPAK AGARWAL

Dr.Boral Subhendu Kumar, Dr.Tushar Kanti Sinha, Dr.DEBASISH BHATTACHARYA

Abstract

Aim–To report antibiotic susceptibility data in Endophthalmitis cases from Eastern India

Method– Retrospective case series. Vitreous biopsy from 293 cases was taken. Antibiotic Susceptibility done by Kirby Bauer method on Culture Positive (CP) bacteria

Results – 84 of CP isolates were bacterial . Commonest bacteria were S.epidermidis and Pseudomonas. For Gram Positive Bacteria (GPB), susceptibility was 100% for Vancomycin, 58%-93% for Fluoroquinolones (FQ). In Gram Negative Bacteria (GNB) susceptibility was 81.25% for Ceftazidime,75%-81.25% for FQ. Both GPB and GNB showed marked resistance to Cephazolin. High resistance for Colistin in GNB (Susceptible in 62.5%)

Conclusion –GPB remains highly susceptible to Vancomycin. GNB shows significant susceptibility to Ceftazidime and FQ. Previously used Cephazoline shows marked resistance. Of paramount concern is significant number of GNB showing resistance for Colistin. Judicious, adequate and responsible prescription of antibiotics is needed