OBJECTIVE: To find out incidence of various types of corneal ulcers and outcome of target specific treatment based on microbiological evaluation. MATERIALS AND METHODS: In a hospital based prospective study over 2 years, 100 cases of corneal ulcer underwent microbiological evaluation of corneal scrapings and culture-guided antimicrobial therapy. RESULT: Most ulcers were found in age between 31-60 years. 76% were males, 24% females, 64% from rural areas, 41% were agricultural laborers with trauma or foreign body being commonest predisposing factors. Among culture positive cases, 67.4% and 22.5% were positive for fungi and bacteria, respectively. 61.6% of cases improved clinically, while 6.6% worsened even after maximum therapy. CONCLUSION: Treating corneal ulcers as an ophthalmic emergency and prompt culture-guided antimicrobial therapy can prevent ocular morbidity and lifelong blindness.
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