Dr.Reena Bharti

Dr. SANJIV GUPTA

Abstract

Aim – to study the survival and outcome in retinoblastoma patients treated at a tertiary care hospital.

methods and results – all patients underwent an examination under anesthesia and classified using international classification of retinoblastoma. All subjects received systemic chemotherapy and local therapy according to the stage of the disease. extraocular presentation and/or residual/recurrent tumour was treated by radiotherapy. All the subjects who followed the treatment protocol were included in the study. mortality rate was highest in group E followed by group D whereas there was no mortality in unilateral group B and group C.

conclusion – neo adjuvant chemotherapy shows promising result in terms of low recurrence rates. latency in diagnosis , higher age at presentation and advanced disease at presentation were associated with high mortality . subjects with early presentation had a favourable outcome and cure was possible after completion of the therapy.