Dr. Annrose Pinheiro

Dr. PRABHU SHANKER M.

Abstract

13 year old girl presented with sudden painless bilateral visual loss since 2 weeks. Visual acuity was perception of light in both eyes. She gave past history of similar episodes at eight and eleven years of age and treated with methylprednisolone pulse therapy elsewhere with some improvement in vision. Previous MRI brain showed small hyperintense focci in corona radiata, periventricular area and cervicomedullary junction .Previous VEP showed prolonged P100 latency. Patient was tested for NMO antibody which came out to be positive and thus confirmed the diagnosis of NMOSD .Patient was then started on IV MP and Azathioprine 50mg. Vision improved to 1/60 bilateral eye.Patient now on followup since 1 year with stable vision and is ambulatory. Although NMO is rare in childhood, cases with recurrent bilateral ON with severe relapse in rapid succession should be evaluated in detail, and the possibility of NMO should be taken into account in the differential diagnosis