Dr.SANKHA SUBHRA CHAUDHURI

Dr. ASIM KUMAR DEY, Dr. MOUSUMI BANERJEE

Abstract

Background: Diabetes mellitus causes neurodegeneration of retina before clinical symptoms and signs of diabetic retinopathy (DR).

Materials and Methods: 160 patients having diabetes mellitus are subjected to Visual Evoked Potential (VEP)

Results: The mean P100 latency of the right and left eyes of cases was 108.61 and 107.63, whereas of controls were 101.03 and 106.35, respectively. The mean P100 amplitude of the right and left eyes of cases was 5.68 and 5.69, whereas those of controls was 6.76 and 6.77, respectively. With respect to duration of diabetes, the mean P100 latency of the right and left eyes for <1 year, 1–2 years, and >2 years was 106.41 and 104.88, 112.19 and 112.15, and 108.38 and 107.31, respectively. The mean P100 amplitude of the right and left eyes for <1 yr, 1–2 yrs, and 2 yrs was 5.42 and 5.68, 5.76 and 5.52, and 5.83 and 5.79, respectively. Conclusion: Our study shows that VEP changes occur in diabetes patients before the appearance of microaneurysm.