Dr. ANURAG KUMAR KASHYAP

Dr. DEEPAK MISHRA, Dr. OM PRAKASH SINGH MAURYA, DR. TANMAY SRIVASTAV

Abstract

AIM:To establish effects of Vitamin D supplementation in dry eye disease(DED) patients.METHOD:This comparative interventional study was conducted between June 2018 to May 2019. DED was established in 40 patients using Tear Breakup Time (TBUT) ,Schirmer score and Ocular Surface Disease Index (OSDI). 20 patients were randomly allocated into two groups. One group was given oral Vitamin D (60,000IU/week for four weeks) and other group was kept on only conventional treatment.RESULTS:Forty patients with 45%men and 55% women were included. Mean serum 25(OH)D level was 20.70±5.91ng/ml. After oral vitamin D supplementation in DED patients, TBUT and Schirmer score were found to be significantly higher at 2 weeks (p < 0.001) and at 6 weeks of treatment (p < 0.001). Also, OSDI score was significantly lower at 6 weeks of treatment (p < 0.001).CONCLUSION:There was positive correlation between serum vitamin D level and dry eye disease.Oral vitamin D supplementation improved TBUT and schirmer score.

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