DR. PRATIROOP GANGOPADHYAY

Dr.DEBABRATA DAS, DR. AVIK DEY SARKAR, Dr. SANJAY KUMAR DAULAT THAKUR

Abstract

Objective: To determine the Retinal Nerve Fiber Layer (RNFL) Thickness changes in Patients with Parkinson’s Disease (PD). Method: RNFL Thickness was assessed in 42 PD patients and 50 healthy age matched controls using a Spectral Domain Optical Coherence Tomography machine from January 2019 – December 2019. Severity of PD was determined using Unified Parkinson Disease Rating Scale (UPDRS) and duration of Bradykinesia and Tremor was noted. Result: The average RNFL thickness in PD patients was 82.06±19.36µm which was significantly thinner the healthy controls which was 95.75±23.27µm (p=0.026). RNFL thinning was found to be directly related to Modified Hoehn and Yahr Staging (UPDRS V) and Schwab and England Scale (UPDRS VI). It was also directly related to duration of Bradykinesia and Tremor. There was no relation to UPDRS I to IV. Conclusion: There is RNFL thinning in patients with Parkinson’s Disease which is directly related to severity and duration of disease.

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