Dr.Nitika Pandey

Dr. APJIT KAUR

Abstract

Aim: To establish the correlation of corneal hysteresis with the clinical profile of patients with thyroid orbitopathy.

Methods: A cross-sectional study was conducted including 90 patients with stage I and II thyroid orbitopathy as group A and 95 controls as group B. Mean CH (Corneal hysteresis) of group A and B were compared. The variation of CH with disease severity, activity, and thyroid status in group A was evaluated.

Results: Mean CH of group A i.e the visco-elastic dampening ability of cornea was significantly lower than that of group B (p < .001). In group A, mean CH of patients with stage 1 severity and CAS<3 was significantly higher than that of patients with stage 2 severity and CAS≥3(p < .001). CH of hypothyroid patients was significantly higher than CH of hyperthyroid patients (p < .01). Conclusion: Corneal hysteresis is negatively correlated with increased disease activity and severity in thyroid orbitopathy.